For Research Use Only — Not for Human Consumption

This product is strictly intended for in-vitro research and laboratory use by qualified researchers. It is not approved for human or veterinary therapeutic use, self-administration, or any clinical application.

Metabolic & Weight Management

AOD-9604

Modified HGH Fragment

5 mg lyophilized powder + 2 mL sterile water

A9Metabolic & Weight Management

Overview

AOD-9604 (Advanced Obesity Drug 9604) is a modified form of HGH Fragment 176-191 featuring an additional disulfide bond that enhances its lipolytic activity and stability. Developed through pharmaceutical research targeting obesity, AOD-9604 has been granted GRAS (Generally Recognized As Safe) status by the FDA for use in food products.

This modified fragment retains the dissociated lipolytic activity of the parent HGH fragment — promoting fat metabolism without activating the growth hormone receptor or stimulating IGF-1 production. Research has additionally uncovered potential applications in cartilage regeneration and osteoarthritis models.

Chemical Profile

PropertyDetails
Molecular Weight~1815.1 Da
Purity≥98% (HPLC verified)
FormLyophilized Powder
AppearanceWhite to off-white powder
SolubilitySterile water, saline
Storage2°C – 8°C, protect from light

Mechanism of Action

AOD-9604 acts through a mechanism similar to HGH Fragment 176-191 but with enhanced potency attributed to its structural modifications. The additional disulfide bond creates a more rigid conformation that increases binding efficiency at the target site on adipocyte membranes.

The peptide primarily interacts with beta-3 adrenergic receptors on adipocytes, stimulating the cAMP/PKA pathway that activates hormone-sensitive lipase. This enzyme catalyzes the hydrolysis of stored triglycerides into glycerol and free fatty acids, facilitating fat mobilization. Simultaneously, AOD-9604 inhibits lipogenic enzymes, preventing the re-esterification of mobilized fatty acids.

Research Applications

  • Enhanced lipolytic activity research
  • Fat metabolism and obesity models
  • Cartilage regeneration studies
  • Osteoarthritis research
  • Beta-3 adrenergic receptor interactions
  • GRAS-status compound research
  • Body composition without GH receptor activation

Handling & Reconstitution

  1. 1Allow the vial and sterile water to reach room temperature (15–25°C).
  2. 2Using a sterile syringe, withdraw the appropriate volume of sterile water.
  3. 3Inject the water slowly along the inside wall of the vial — do not spray directly onto the powder.
  4. 4Gently swirl the vial until the powder is fully dissolved. Do not shake vigorously.
  5. 5Once reconstituted, store at 2°C – 8°C. Protect from light.
  6. 6Use within 28 days after reconstitution.
  7. 7Do not freeze reconstituted solution.

Product Specifications

  • 1 × Vial (2R) containing AOD-9604 lyophilized powder (5 mg)
  • 1 × Ampoule Sterile Water for Injection (2 mL)
  • Storage: 2°C – 8°C, protect from light
  • Shelf life: 24 months (unopened, properly stored)

Ingredients

Advanced Obesity Drug 9604 (5 mg), Mannitol, Sucrose

Certificate of Analysis

Full CoA with HPLC purity data and mass spectrometry confirmation is available for every batch.

Request CoA

Related Products

HGH Fragment 176-191

Lipolytic Peptide Fragment

MOTS-c

Mitochondrial-Derived Peptide

Semaglutide

GLP-1 Receptor Agonist

Disclaimer

This product is intended for research and laboratory use only. Not for human consumption. LyoGenix Labs Pvt. Ltd. does not condone or promote the use of these compounds outside of legitimate research.

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